Dan Barker was set to face the current mayor, Labour’s Andy Burnham, as the Conservative candidate in May.
The former housing minister is believed to have told his friends that he will run for Tory leader when the job comes up.
A number of well-known Tories are being confronted by a stark reality - and the likes of Jacob Rees-Mogg face a daunting prospect.
The author and columnist said he wants to offer an alternative to Sir Keir Starmer’s party in key seats.
The YouGov poll for The Times puts the Conservatives at Liz Truss lows, with the right-wing threat of Reform a major cause for concern.
"The work to unseat the Deputy Prime Minister starts now."
"It does seem to me... the British public is actually kinder and more concerned than this government. So this government doesn't represent the public anymore", Baroness Jenny Jones said.
Speculation is rife that rebel Conservative MPs are lining up potential successors to replace the Prime Minister should he face a no confidence test.
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